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Recommendations of the Advisory Vaccine Committee
Anti-Flu Vaccination Campaign 2005-2006
released 18 November 2005
This report updates the
recommendations on prevention of the influenza Advisory Vaccine
Committee (AVC) performed in 2.004.
Introduction
Influenza produces a high annual morbidity in pediatric population.
Children represent the group of age with highest rates of incidence. At
the moment the AVC does not advise the systematic vaccination of
influenza to healthy children. Previous to this recommendation there
will be necessary to make epidemiological studies in our country that
value the impact of the influenza disease in children, their role as
source of infection for adults at risk, and therefore the efficiency of
the systematic vaccination in our area. The AVC recommends performing
studies that allow us to know the incidence rates and hospitalization
due to its annual epidemic season. However, and based on the existing
evidences, the AVC considers that any children older than six months of
age can be vaccinated when parents request for it, although with
priority of access to the vaccine for the children at risk.
The World Health Organization communicates that influenza vaccine
prepared for the 2005-2006 season must be included:
-
A/California/7/2004 (H3N2)-like
virus
-
A/New Caledonia/20/1999
(H1N1)-like virus
-
B/Shanghai/361/2002-like
virus
Alternatively it can be used
for the vaccine elaboration in this season: A/New York/55/2004; B/Jilin/70/2003;y
B/Jiangsu/10/2003.
Children at risk.- We
consider children at risk those who by their co morbidity pathology, or
by their characteristics, constitute a group for which the infection by
influenza virus can produce a serious worsening of their pathology.
1. Recommendations
1. Children with
chronic diseases:
a. Chronic lung
diseases, including asthma.
b. Serious cardiovascular diseases.
c. Neuromuscular diseases that produce a respiratory commitment
by himself or by a difficulty of respiratory secretion
mobilization.
d. Any statement of weakened immune system
e. Children who receive a long-term treatment with
acetylsalicylic acid.
2. Adults who can
transmit flu to children who live with them:
a. Pregnant women
who are going to give birth during the months of the annual
epidemic season (November to March).
b. Relatives and people who live with children of any age, who
are fitted in the indications gathered in the fist point.
c. Sanitary Personnel that exerts its work with children in
hospitals, private centers of health or doctor's offices.
d. Workers of institutions of children with a physical or a
psychic disability
e. Workers of day-care centers.
NOTE: Mothers who breast-feed
to their children can receive the vaccine.
2- Dosage
|
|
Dose |
Way administration |
number |
type |
|
6-35 months
3-8 years
9-12 years
|
0.25ml
0.5 ml
0.5 ml |
IM
IM
IM |
1-2*
1-2*
1 |
Subunits
virus vaccine |
Adolescents and adults
|
0.5 ml |
IM |
1 |
Whole virus or
subunits virus vaccine
|
|
*Two doses in children
younger than 9y, who haven’t received the vaccine before,
with an interval between two doses of at least 4 weeks |
3-Administration
intramuscular.
4- Contrainditions:
a.
Egg allergy
b.
Allergy to other vaccine components
c.
Children younger than six months
d.
Children who have suffered Guillain-Barre syndrome
5-
References:
-Harper SA,
Fukuda K, Uyeki TM, Cox NJ, Bridges CB, for the Centers for Disease
Control and Prevention (CDC) Advisory Committee on Immunization
Practices (ACIP). Prevention and control of influenza: Recommendations
of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm
Rep 2004;53:1-40.
-Neuzil KM,
Mellen BG, Wright PF, Mitchel EF Jr, Griffin MR. The effect of influenza
on hospitalizations, outpatient visits, and courses of antibiotics in
children. N Engl J Med 2000;342:225-31.
-Izurieta HS,
Thompson WW, Kramarz P, et al. Influenza and the rates of
hospitalization for respiratory disease among infants and young
children. N Engl J Med 2000;342:232-9.
-Neuzil KM, Zhu Y, Griffen MR, et al.
Burden of interpandemic influenza in children younger than 5 years: A
25-year prospective study. J Infect Dis 2002;185:147-52.
-American
Academy of Pediatrics, Committee on Infectious Diseases. Recommendations
for influenza immunization of children. Pediatrics 2004;113:1441-7.
-Sharon G.
Humiston, Peter G. Szilagyi, Marika K. Iwane, Stanley J. Schaffer,
Jeanne Santoli, Laura Shone, Richard Barth, BS Thomas McInerny, Benjamin
Schwartz, The Feasibility of Universal Influenza Vaccination for Infants
and Toddlers Arch Pediatr Adolesc Med. 2004;158:867-874
-Public
Health Agency of Canada National Advisory Committee om Immunization
(NACI) Statement on influenza vaccination for the 2005-2006 season.
CCDR;15 June 2005,Volume 31
-Prevention
and Control of Influenza Recommendations of the Advisory Committee on
Immunization Practices (ACIP)
MMWR
July 29,
2005 / 54(RR08);1-40
-National Advisory Committee on Immunization. Statement on influenza
vaccination for the 2005-2006 season. CCDR 2005;31(ACS-6):1-2
-High levels of clinical influenza activity on the Iberian Peninsula and
neighbouring countries. EISS
Weekly Electronic Bulletin.
Nº136.17/01/2005. En:
http://www.eiss.org/cgi-files/bulletinv2.cgi
Attachment
The following ones are the vaccines registered in Spain
and authorized by summary product characteristics in children older than
6 months of age:
1. Inactivated virus vaccines:
a. Vacuna antigripal fraccionada polivalente
LETI
b. Fluarix® GSK
c. Gripavac® Sanofi Pasteur MSD
d. Vacuna antigripal Pasteur Sanofi Pasteur MSD
2. Subunits virus vaccines:
a. Chiroflu® Esteve
b. Influvac® Solvay Pharma
3. Subunits Virosomic vaccines:
a. Inflexal V®Berna
Biotech
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